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Effect of Intensity of Oral Anticoagulation on Stroke Severity and Mortality in Atrial Fibrillation
NEJM 349:1019-1026, Hylek,E.M.,et al, 2003
See this aricle in Pubmed

Article Abstract
Among patients with nonvalvular atrial fibrillation, anticoagulation that results in an INR of 2.0 or greater reduces not only the frequency of ischemic stroke but also its severity and the risk of death from stroke. Our findings provide further evidence against the use of lower INR target levels in patients with atrial fibrillation.
 
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anticoagulant,treatment
atrial fibrillation
cerebrovascular accident
cerebrovascular accident,prevention of
cerebrovascular accident,severity
coumarin
INR value,time in range
INR values
mortality
prevention of neurologic disorders
treatment of neurologic disorder

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